Berberine Optim® – Advanced Metabolic, Glucose & Cardiovascular Support - Nutrinat Evolution

Why we selected it

Berberine is one of the most clinically researched plant compounds for metabolic health, yet most traditional forms suffer from low solubility and poor absorption. Berberine Optim® uses a full-spectrum Berberis vulgaris root extract that improves solubility and tolerability, making it more efficient than standard berberine forms (page 1) .

This formula is supported by four synergistic mechanisms:

1. Supports healthy blood glucose & insulin sensitivity

Berberine activates AMPK, a key metabolic regulator that helps improve glucose uptake and support insulin signalling (page 2) .
The result may include:

• Improved glucose utilisation

• Better insulin sensitivity

• Support for healthy fasting glucose levels

2. Supports lipid metabolism & cardiovascular function

Berberine, grape seed proanthocyanidins, and chromium may jointly support:

• Reduced LDL cholesterol and triglycerides

• Improved endothelial function

• Better cardiovascular resilience (page 1)

3. Aids weight-management efforts

By influencing AMPK and fatty-acid metabolism, berberine may help reduce body fat and support healthy weight management (page 2) .

4. Multi-pathway antioxidant protection

R-alpha lipoic acid is described as an “antioxidant of antioxidants,” capable of regenerating vitamins C & E, CoQ10, and glutathione (page 1) .
This supports:

• Mitochondrial energy metabolism

• Reduction of oxidative stress

• Cellular health and metabolic function

Why it fits the Corecel curation standard

✔ Full-spectrum berberine extract for improved bioavailability
✔ R-alpha lipoic acid (the biologically active isomer)
✔ Chromium picolinate (clinically relevant form for glucose metabolism)
✔ Clean formula with no unnecessary additives
✔ Strong scientific backing and multi-mechanism metabolic support